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Assuming oral bioavailability of ~1% with current formulations that have been FDA-approved compared to injections of the same peptide, the cost-of-goods argument becomes unsustainable for most candidates that might be considered for conversion to the oral route

Dermatol Res

Description Epithalon Peptide 10mg (Lyophilized Peptide) For Research Use Only Epithalon (also known as Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the naturally occurring pineal gland peptide Epithalamin

The resulting IL-6/sIL-6R complex can activate gp130 on nearly all cell types, including those that do not express mIL-6R, thereby dramatically broadening the cellular targets of IL-6

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